| DeShone Kizer | QB | Notre Dame | RSO | Has entered draft |
| Deshaun Watson | QB | Clemson | JR | Will enter draft |
| Brad Kaaya | QB | Miami | JR | Will enter draft |
| Mitch Trubisky | QB | North Carolina | JR | Will enter draft |
| Mason Rudolph | QB | Oklahoma State | JR | Will return to school |
| Pat Mahomes | QB | Texas Tech | JR | Will enter draft |
| Luke Falk | QB | Washington State | JR | Appears to be headed back to school |
| Baker Mayfield | QB | Oklahoma | JR | Is returning to school |
| JT Barrett | QB | Ohio State | JR | Will return to school |
| Len Fournette | RB | LSU | JR | Will enter draft |
| Christian McCaffrey | RB | Stanford | JR | Will enter draft |
| Dalvin Cook | RB | Florida State | JR | Will enter draft |
| Royce Freeman | RB | Oregon | JR | Will return to school |
| D'Onta Foreman | RB | Texas | JR | Has declared for draft |
| Nick Chubb | RB | Georgia | JR | Will return to school |
| Samaje Perine | RB | Oklahoma | JR | Will enter draft |
| Jalen Hurd | RB | Tennessee | JR | Left Tennessee and reportedly plans to transfer |
| Wayne Gallman | RB | Clemson | JR | Will enter draft |
| James Conner | RB | Pittsburgh | JR | Has entered draft |
| Elijah Hood | RB | North Carolina | JR | Changed his mind and will enter draft |
| Sony Michel | RB | Georgia | JR | Will return to school |
| Alvin Kamara | RB | Tennessee | JR | Will enter draft |
| Joe Mixon | RB | Oklahoma | RSO | Will enter draft |
| Brian Hill | RB | Wyoming | JR | Has entered draft |
| Jeremy McNichols | RB | Boise State | JR | Will enter draft |
| Tarean Folston | RB | Notre Dame | JR | Will enter draft |
| Marlon Mack | RB | South Florida | JR | Will enter draft |
| Curtis Samuel | RB | Ohio State | JR | Will enter draft as WR or RB |
| Aaron Jones | RB | UTEP | JR | Will enter draft |
| Justin Jackson | RB | Northwestern | JR | Will return to school |
| Devine Redding | RB | Indiana | JR | Will enter draft |
| Khalid Hill | FB | Michigan | JR | Will return to school |
| JuJu Smith-Schuster | WR | Southern California | JR | Will enter draft |
| Mike Williams | WR | Clemson | JR | Will enter draft |
| John Ross | WR | Washington | JR | Will enter draft |
| Darren Carrington | WR | Oregon | JR | Will return to school |
| Isaiah Ford | WR | Virginia Tech | JR | Will enter draft |
| Malachi Dupree | WR | LSU | JR | Will enter draft |
| Travis Rudolph | WR | Florida State | JR | Will enter draft |
| Courtland Sutton | WR | SMU | RSO | Will return to school |
| James Washington | WR | Oklahoma State | JR | Will return to school |
| Artavis Scott | WR | Clemson | JR | Will enter draft |
| Simmie Cobbs | WR | Indiana | JR | |
| Ricky Seals-Jones | WR | Texas A&M | JR | Will enter draft |
| Chris Godwin | WR | Penn State | JR | Will enter draft |
| KD Cannon | WR | Baylor | JR | Will enter draft |
| Damore'ea Stringfellow | WR | Mississippi | JR | Has declared for draft |
| Josh Malone | WR | Tennessee | JR | Will enter draft |
| Devonte Boyd | WR | UNLV | JR | |
| Chad Hansen | WR | California | JR | Will enter draft |
| Ardarius Stewart | WR | Alabama | JR | Will enter draft |
| Jerome Lane | WR | Akron | JR | Is entering draft |
| Carlos Henderson | WR | Louisiana Tech | JR | Will enter draft |
| Michael Clark | WR | Marshall | RSO | Will enter draft |
| Bucky Hodges | TE | Virginia Tech | JR | Will enter draft |
| David Njoku | TE | Miami | RSO | Will enter draft |
| Durham Smythe | TE | Notre Dame | JR | Appears headed back to school |
| Jeb Blazevich | TE | Georgia | JR | |
| Adam Breneman | TE | UMass | JR | Will return to school |
| Cam Serigne | TE | Wake Forest | JR | Will return to school |
| Mike Gesicki | TE | Penn State | JR | Will return to school |
| Cam Robinson | OT | Alabama | JR | Will enter draft |
| Mike McGlinchey | OT | Notre Dame | JR | Has already said he will return to school |
| Rod Johnson | G/T | Florida State | JR | Will enter draft |
| Orlando Brown | OT | Oklahoma | RSO | Says he's staying |
| Tyrell Crosby | OT | Oregon | JR | Will return to school |
| Ryan Ramczyk | OT | Wisconsin | JR | Will enter draft |
| Garrett Bolles | OT | Utah | JR | Will enter draft |
| Martinas Rankin | OT | Mississippi State | JR | |
| Billy Price | OG | Ohio State | JR | Will return to school where he will likely make switch to C |
| Cody O'Connell | G/T | Washington State | JR | Will return to school |
| Tyrone Crowder | OG | Clemson | JR | Will return to school |
| Braden Smith | OG | Auburn | JR | Will return to school |
| Quenton Nelson | OG | Notre Dame | RSO | Reportedly leaning toward staying |
| Scott Quessenberry | OG | UCLA | JR | |
| Mason Cole | C | Michigan | JR | Will return to school |
| Frank Ragnow | C | Arkansas | JR | Returning to school |
| Brian Allen | C | Michigan State | JR | |
| Coleman Shelton | C | Washington | JR | |
| Myles Garrett | DE | Texas A&M | JR | Will enter draft |
| Derek Barnett | DE | Tennessee | JR | Will enter draft |
| Carl Lawson | DE | Auburn | JR | Will enter draft |
| Charles Harris | DE | Missouri | JR | Has entered draft |
| Da'Shawn Hand | DE/5T | Alabama | JR | |
| Sam Hubbard | DE | Ohio State | RSO | Will return to school |
| Solomon Thomas | DE | Stanford | RSO | Will enter draft |
| Tyquan Lewis | DE | Ohio State | JR | Will return to school |
| Harold Landry | DE | Boston College | JR | Will return to school |
| Andrew Brown | DE | Virginia | JR | Will return to school |
| Duke Ejiofor | DE | Wake Forest | JR | Will return to school |
| Jacob Pugh | DE | Florida State | JR | |
| Kentavius Street | DE | NC State | JR | |
| Malik McDowell | DT | Michigan State | JR | Has entered draft |
| Lowell Lotulelei | DT | Utah | JR | |
| Elijah Qualls | DT | Washington | JR | Will enter draft |
| Charles Walker | DT | Oklahoma | JR | Has left school to prepare for draft |
| Eddie Vanderdoes | DT | UCLA | JR | Has declared for draft |
| Caleb Brantley | DT | Florida | JR | Will enter draft |
| Davon Godchaux | DT | LSU | JR | Will enter draft |
| Vince Taylor | DT | Oklahoma State | JR | Will enter draft |
| Derrick Nnadi | DT | Florida State | JR | Returning to school |
| Vita Vea | DT | Washington | RSO | Will return to school |
| Maurice Hurst | DT | Michigan | JR | Will return to school |
| Raekwon McMillan | ILB | Ohio State | JR | Will enter draft |
| Anthony Walker | ILB | Northwestern | JR | Will enter draft |
| Azeem Victor | ILB | Washington | JR | Says he's staying after breaking leg 06/11 |
| Alex Anzalone | ILB | Florida | JR | Entered draft despite missing back half of seasn with broken arm |
| Tim Kimbrough | ILB | Georgia | JR | Has said he will enter the draft |
| Micah Kiser | ILB | Virginia | JR | Will return to school |
| Augie Sanchez | ILB | South Florida | JR | |
| Josey Jewell | ILB | Iowa | JR | Is returning to school |
| Zach Cunningham | OLB/ILB | Vanderbilt | JR | Will enter draft |
| TJ Watt | OLB | Wisconsin | JR | Will enter draft |
| Marquis Haynes | OLB | Mississippi | JR | Has decided to return to school |
| Dante Booker | OLB | Ohio State | JR | |
| Davin Bellamy | OLB | Georgia | JR | Will return to school |
| James Hearns | OLB | Louisville | JR | |
| Lorenzo Carter | OLB | Georgia | JR | Will return to school |
| Elijah Lee | OLB | Kansas State | JR | Will enter draft |
| Bradley Chubb | OLB | NC State | JR | Will return to school |
| Mike McCray | OLB | Michigan | JR | Will return to school |
| Jabrill Peppers | SS/OLB | Michigan | RSO | Family is reportedly interviewing agents |
| Jamal Adams | FS | LSU | JR | Will enter draft |
| Budda Baker | FS | Washington | JR | Will enter draft |
| Malik Hooker | FS | Ohio State | RSO | Will enter draft |
| Marcus Williams | FS | Utah | JR | Will enter draft |
| Quin Blanding | FS | Virginia | JR | Is returning to school |
| Dominick Sanders | SS | Georgia | JR | Will return to school |
| Montae Nicholson | SS | Michigan State | JR | Will enter draft |
| Steven Parker | SS | Oklahoma | JR | |
| Marcus Allen | FS | Penn State | JR | Will return to school |
| Armani Watts | FS | Texas A&M | JR | Has decided to return to school |
| Evan Berry | SS/KR | Tennessee | JR | Knee injury could cloud draft plans |
| Jaleel Wadood | SS | UCLA | JR | |
| Tray Matthews | SS | Auburn | JR | Will return to school |
| Teez Tabor | CB | Florida | JR | Will enter draft |
| Marshon Lattimore | CB | Ohio State | RSO | Will enter draft |
| Marlon Humphrey | CB | Alabama | RSO | Will enter draft |
| Sidney Jones | CB | Washington | JR | Will enter draft |
| Adoree Jackson | CB | Southern California | JR | Will enter draft |
| Gareon Conley | CB | Ohio State | JR | Will enter draft |
| Brandon Facyson | CB | Virginia Tech | JR | Will return to school |
| Quincy Wilson | CB | Florida | JR | Will enter draft |
| Jordan Thomas | CB | Oklahoma | JR | Has decided to return to school |
| JK Scott | P | Alabama | JR | Will return to school |
| Daniel Carlson | PK | Auburn | JR | Will return to school |
