First round
| # | Team | Player | POS | School |
|---|---|---|---|---|
| Cleveland | Myles Garrett | DE | Texas A&M | |
| Chicago (from San Francisco) | Mitch Trubisky | QB | North Carolina | |
| San Francisco (from Chicago) | Solomon Thomas | DE | Stanford | |
| Jacksonville | Leonard Fournette | RB | LSU | |
| Tennessee (from LA Rams) | Corey Davis | WR | Western Michigan | |
| NY Jets | Jamal Adams | SS | LSU | |
| LA Chargers | Mike Williams | WR | Clemson | |
| Carolina | Christian McCaffrey | RB | Stanford | |
| Cincinnati | John Ross | WR | Washington | |
| Kansas City (from Buffalo) | Patrick Mahomes | QB | Texas Tech | |
| New Orleans | Marshon Lattimore | CB | Ohio State | |
| Houston (from Philadelphia thru Cleveland) | Deshaun Watson | QB | Clemson | |
| Arizona | Haason Reddick | LB | Temple | |
| Philadelphia (from Minnesota) | Derek Barnett | DE | Tennessee | |
| Indianapolis | Malik Hooker | FS | Ohio State | |
| Baltimore | Marlon Humphrey | CB | Alabama | |
| Washington | Jonathan Allen | DE | Alabama | |
| Tennessee | Adoree Jackson | CB | Southern California | |
| Tampa Bay | OJ Howard | TE | Alabama | |
| Denver | Garrett Bolles | OT | Utah | |
| Detroit | Jarrad Davis | LB | Florida | |
| Miami | Charles Harris | DE | Missouri | |
| NY Giants | Evan Engram | TE | Mississippi | |
| Oakland | Gareon Conley | CB | Ohio State | |
| Cleveland (from Houston) | Jabrill Peppers | SS | Michigan | |
| Atlanta (from Seattle) | Takk McKinley | DE/OLB | UCLA | |
| Buffalo (from Kansas City) | Tre'Davious White | CB/KR | LSU | |
| Dallas | Taco Charlton | DE | Michigan | |
| Cleveland (from Green Bay) | David Njoku | TE | Miami | |
| Pittsburgh | TJ Watt | OLB | Wisconsin | |
| San Francisco (from Atlanta thru Seattle) | Reuben Foster | ILB | Alabama | |
| New Orleans (from New England) | Ryan Ramczyk | OT | Wisconsin |
Second round
| 33 | Green Bay (from Cleveland) | Kevin King | CB | Washington |
| 34 | Jacksonville (from San Francisco thru Seattle) | Cam Robinson | OT | Alabama |
| 35 | Seattle (from Jacksonville) | Malik McDowell | DT | Michigan State |
| 36 | Arizona (from Chicago) | Budda Baker | FS | Washington |
| 37 | Buffalo (from LA Rams) | Zay Jones | WR | East Carolina |
| 38 | LA Chargers | Forrest Lamp | OG | Western Kentucky |
| 39 | NY Jets | Marcus Maye | FS | Florida |
| 40 | Carolina | Curtis Samuel | WR | Ohio State |
| 41 | Minnesota (from Cincinnati) | Dalvin Cook | RB | Florida State |
| 42 | New Orleans | Marcus Williams | FS | Utah |
| 43 | Philadelphia | Sidney Jones | CB | Washington |
| 44 | LA Rams (from Buffalo) | Gerald Everett | TE | South Florida |
| 45 | Chicago (from Arizona) | Adam Shaheen | TE | Ashland |
| 46 | Indianapolis | Quincy Wilson | CB | Florida |
| 47 | Baltimore | Tyus Bowser | OLB | Houston |
| 48 | Cincinnati (from Minnesota) | Joe Mixon | RB | Oklahoma |
| 49 | Washington | Ryan Anderson | OLB | Alabama |
| 50 | Tampa Bay | Justin Evans | FS | Texas A&M |
| 51 | Denver | Demarcus Walker | DE | Florida State |
| 52 | Cleveland (from Tennessee) | DeShone Kizer | QB | Notre Dame |
| 53 | Detroit | Teez Tabor | CB | Florida |
| 54 | Miami | Raekwon McMillan | LB | Ohio State |
| 55 | NY Giants | Dalvin Tomlinson | DT | Alabama |
| 56 | Oakland | Obi Melifonwu | FS | UConn |
| 57 | Houston | Zach Cunningham | LB | Vanderbilt |
| 58 | Seattle | Ethan Pocic | C | LSU |
| 59 | Kansas City | Tanoh Kpassagnon | DE | Villanova |
| 60 | Dallas | Chidobe Awuzie | CB | Colorado |
| 61 | Green Bay | Josh Jones | FS | North Carolina State |
| 62 | Pittsburgh | JuJu Smith-Schuster | WR | Southern California |
| 63 | Buffalo (from Atlanta) | Dion Dawkins | G/T | Temple |
| 64 | Carolina (from New England) | Taylor Moton | G/T | Western Michigan |
Third round
| 65 | Cleveland | Larry Ogunjobi | DT | Charlotte |
| 66 | San Francisco | Ahkello Witherspoon | CB | Colorado |
| 67 | New Orleans (from Chicago thru San Francisco) | Alvin Kamara | RB | Tennessee |
| 68 | Jacksonville | Dawaune Smoot | DE | Illinois |
| 69 | LA Rams | Cooper Kupp | WR | Eastern Washington |
| 70 | Minnesota (from NY Jets) | Pat Elflein | C | Ohio State |
| 71 | LA Chargers | Dan Feeney | OG | Indiana |
| 72 | Tennessee (from Carolina thru New England) | Taywan Taylor | WR | Western Kentucky |
| 73 | Cincinnati | Jordan Willis | DE | Kansas State |
| 74 | Baltimore (from Philadelphia) | Chris Wormley | 5T | Michigan |
| 75 | Atlanta (from Buffalo) | Duke Riley | LB | LSU |
| 76 | New Orleans | Alex Anzalone | LB | Florida |
| 77 | Carolina (from Arizona) | Daeshon Hall | DE | Texas A&M |
| 78 | Baltimore | Tim Williams | OLB | Alabama |
| 79 | NY Jets (from Minnesota) | ArDarius Stewart | WR | Alabama |
| 80 | Indianapolis | Tarell Basham | DE | Ohio |
| 81 | Washington | Fabian Moreau | CB | UCLA |
| 82 | Denver | Carlos Henderson | WR | Louisiana Tech |
| 83 | New England (from Tennessee) | Derek Rivers | DE | Youngstown State |
| 84 | Tampa Bay | Chris Godwin | WR | Penn State |
| 85 | New England (from Detroit) | Antonio Garcia | OT | Troy |
| 86 | Kansas City (from Miami thru Minnesota) | Kareem Hunt | RB | Toledo |
| 87 | NY Giants | Davis Webb | QB | California |
| 88 | Oakland | Eddie Vanderdoes | DT | UCLA |
| 89 | Houston | D'onta Foreman | RB | Texas |
| 90 | Seattle | Shaq Griffin | CB | Central Florida |
| 91 | LA Rams (from Kansas City thru Buffalo) | John Johnson | FS | Boston College |
| 92 | Dallas | Jourdan Lewis | CB | Michigan |
| 93 | Green Bay | Montravius Adams | DT | Auburn |
| 94 | Pittsburgh | Cameron Sutton | CB | Tennessee |
| 95 | Seattle (from Atlanta) | Delano Hill | FS | Michgan |
| 96 | Detroit (from New England) | Kenny Golladay | WR | Nebraska |
| 97c | Miami | Cordrea Tankersley | CB | Clemson |
| 98c | Arizona (from Carolina) | Chad Williams | WR | Grambling |
| 99c | Philadelphia (from Baltimore) | Rasul Dougals | CB | West Virginia |
| 100c | Tennessee (from LA Rams) | Jonnu Smith | TE | Florida International |
| 101c | Denver | Brendan Langley | CB | Lamar |
| 102c | Seattle | Nazair Jones | DT | North Carolina |
| 103c | New Orleans (from Cleveland thru New England) | Trey Hendrickson | DE | Florida Atlantic |
| 104c | San Francisco (from Kansas City) | CJ Beathard | QB | Iowa |
| 105c | Pittsburgh | James Conner | RB | Pittsburgh |
| 106c | Seattle | Amara Darboh | WR | Michigan |
| 107c | Tampa Bay (NY Jets) | Kendell Beckwith | LB | LSU |
Fourth round
| 108 | Green Bay (from Cleveland) | Vince Biegel | OLB | Wisconsin |
| 109 | Minnesota (from San Francisco) | Jaleel Johnson | DT | Iowa |
| 110 | Jacksonville | DeDe Westbrook | WR | Oklahoma |
| 111 | Seattle (from Chicago thru San Francisco) | Tedric Thompson | FS | Colorado |
| 112 | Chicago (LA Rams) | Eddie Jackson | SS | Alabama |
| 113 | LA Chargers | Rayshawn Jenkins | SS | Miami |
| 114 | Washington (from NY Jets) | Samaje Perine | RB | Oklahoma |
| 115 | Arizona (from Carolina) | Dorian Johnson | OG | Pittsburgh |
| 116 | Cincinnati | Carl Lawson | DE | Auburn |
| 117 | LA Rams (from Buffalo thru Chicago) | Josh Reynolds | WR | Texas A&M |
| 118 | Philadelphia | Mack Hollins | WR | North Carolina |
| 119 | Chicago (from Arizona) | Tarik Cohen | RB | North Carolina A&T |
| 120 | Minnesota | Ben Gedeon | LB | Michigan |
| 121 | San Francisco (from Indianapolis) | Joe Williams | RB | Utah |
| 122 | Baltimore | Nico Siragusa | OG | San Diego State |
| 123 | Washington | Montae Nicholson | SS | Michigan State |
| 124 | Detroit (from Tennessee thru New England) | Jalen Reeves-Maybin | OLB | Tennessee |
| 125 | LA Rams (from Tampa Bay thru NY Jets) | Samson Ebukan | OLB | Eastern Washington |
| 126 | Cleveland (from Denver) | Howard Wilson | CB | Houston |
| 127 | Detroit | Michael Roberts | TE | Toledo |
| 128 | Cincinnati (from Miami thru Minnesota) | Josh Malone | WR | Tennessee |
| 129 | Oakland | David Sharpe | OT | Florida |
| 130 | Houston | Julien Davenport | OT | Bucknell |
| 131 | New England (from Seattle) | Deatrich Wise | DE | Arkansas |
| 132 | Philadelphia (from Kansas City thru Minnesota) | Donnel Pumphrey | RB | San Diego State |
| 133 | Dallas | Ryan Switzer | WR | North Carolina |
| 134 | Green Bay | Jamal Williams | RB | BYU |
| 135 | Pittsburgh | Josh Dobbs | QB | Tennessee |
| 136 | Atlanta | Sean Harlow | OG | Oregon State |
| 137 | Indianapolis (from New England) | Zach Banner | G/T | USC |
| 138c | Cincinnati | Ryan Glasgow | DT | Michigan |
| 139c | Kansas City (from Cleveland thru Philadelphia and Minnesota) | Jehu Chesson | WR | Michigan |
| 140 | NY Giants | Wayne Gallman | RB | Clemson |
| 141c | NY Jets (from LA Rams) | Chad Hansen | WR | California |
| 142c | Houston (from Cleveland) | Carlos Watkins | DT | Clemson |
| 143c | Indianapolis (from San Francisco) | Marlon Mack | RB | South Florida |
| 144c | Indianapolis | Grover Stewart | DT | Albany State |
Fifth round
| 145 | Denver (from Cleveland) | Jake Butt | TE | Michigan |
| 146 | San Francisco | George Kittle | TE | Iowa |
| 147 | Chicago | Jordan Morgan | OG | Kutztown State |
| 148 | Jacksonville | Blair Brown | LB | Ohio |
| 149 | Atlanta (from LA Rams thru Buffalo) | Damontae Kazee | CB | San Diego State |
| 150 | NY Jets | Jordan Leggett | TE | Clemson |
| 151 | LA Chargers | Des King | FS | Iowa |
| 152 | Carolina | Corn Elder | CB | Miami |
| 153 | Cincinnati | Jake Elliott | PK | Memphis |
| 154 | Washington (from New Orleans) | Jeremy Sprinkle | TE | Arkansas |
| 155 | Tennessee (from Philadelphia) | Jayon Brown | LB | UCLA |
| 156 | Atlanta (from Buffalo) | Brian Hill | RB | Wyoming |
| 157 | Arizona | Will Holden | G/T | Vanderbilt |
| 158 | Indianapolis | Nate Hairston | CB | Temple |
| 159 | Baltimore | Jermaine Eluemunor | G/T | Texas A&M |
| 160 | Cleveland (from Minnesota thru NY Jets) | Rod Johnson | OT | Florida State |
| 161 | Indianapolis (from Washington thru SF) | Anthony Walker | LB | Northwestern |
| 162 | Tampa Bay | Jeremy McNichols | RB | Boise State |
| 163 | Buffalo (from Denver thru New England) | Matt Milano | OLB | Boston College |
| 164 | Miami (from Tennessee thru Philadelphia) | Ike Asiata | OG | San Diego State |
| 165 | Detroit | Jamal Agnew | CB | San Diego |
| 166 | Philadelphia (from Miami) | Shelton Gibson | WR | West Virginia |
| 167 | NY Giants | Avery Moss | DE | Younstown State |
| 168 | Oakland | Marquel Lee | LB | Wake Forest |
| 169 | Houston | Treston DeCoud | CB | Oregon State |
| 170 | Minnesota (from Kansas City) | Rodney Adams | WR | South Florida |
| 171 | Buffalo (from Dallas) | Nate Peterman | QB | Pittsburgh |
| 172 | Denver (from Green Bay) | Ike McKenzie | WR | Georgia |
| 173 | Pittsburgh | Brian Allen | CB | Utah |
| 174 | Atlanta | Eric Saubert | TE | Drake |
| 175 | Green Bay (from New England thru Cleveland) | DeAngelo Yancey | WR | Purdue |
| 176c | Cincinnati | JJ Dielman | C | Utah |
| 177c | San Francisco (from Denver) | Trent Taylor | WR | Louisiana Tech |
| 178c | Miami | Davon Godchaux | DT | LSU |
| 179c | Arizona | TJ Logan | RB | North Carolina |
| 180c | Minnesota (from Kansas City) | Danny Ididora | OG | Miami |
| 181c | NY Jets (from Cleveland) | Dylan Donahue | OLB | West Georgia |
| 182c | Green Bay | Aaron Jones | RB | UTEP |
| 183c | Kansas City (from New England) | Ukeme Eligwe | LB | Georgia Southern |
| 184c | Philadelphia (from Miami) | Nate Gerry | SS | Nebraska |
Sixth round
| 185 | Cleveland | Caleb Brantley | DT | Florida |
| 186 | Baltimore (from San Francisco) | Chuck Clark | SS | Virginia Tech |
| 187 | Seattle (from Jacksonville) | Mike Tyson | SS | Cincinnati |
| 188 | NY Jets (from Chicago thru Houston and Cleveland) | Elijah McGuire | RB | Louisiana-Lafayette |
| 189 | LA Rams | Tanzel Smart | DT | Tulane |
| 190 | LA Chargers | Sam Tevi | OT | Utah |
| 191 | Dallas (from NY Jets) | Xavier Woods | FS | Louisiana Tech |
| 192 | Carolina | Alex Armah | DE | West Georgia |
| 193 | Cincinnati | Jordan Evans | SS | Oklahoma |
| 194 | Miami (from Philadelphia) | Vince Taylor | DT | Oklahoma State |
| 195 | Buffalo | Tanner Vallejo | LB | Boise State |
| 196 | New Orleans | Al-quadin Muhammad | DE | Miami |
| 197 | NY Jets (from Arizona thru Chicago) | Jeremy Clark | CB | Michigan |
| 198 | San Francisco (from Baltimore) | DJ Jones | DT | Mississippi |
| 199 | Washington (from Minnesota) | Chase Roullier | C/G | Wyoming |
| 200 | NY Giants (from Indianapolis thru New England and Tennessee) | Adam Bisnowaty | OT | Pittsburgh |
| 201 | Minnesota (from Washington) | Bucky Hodges | WR | Virginia Tech |
| 202 | San Francisco (from Denver) | Pita Taumoepena | LB | Utah |
| 203 | Denver (from Tennessee) | D'angelo Henderson | RB | Coastal Carolina |
| 204 | NY Jets (from Tampa Bay) | Derrick Jones | CB | Mississippi |
| 205 | Detroit | Jeremiah Ledbetter | DE | Arkansas |
| 206 | LA Rams (from Miami) | Sam Rogers | FB | Virginia Tech |
| 207 | Cincinnati (from NY Giants) | Brandon Wilson | CB | Houston |
| 208 | Arizona (from Oakland) | Jonathan Ford | SS | Auburn |
| 209 | Washington (from Houston) | Robert Davis | WR | Georgia State |
| 210 | Seattle | Justin Senior | OT | Mississippi State |
| 211 | New England (from Dallas) | Conor McDermott | OT | UCLA |
| 212 | Green Bay | Kofi Amichia | OT | South Florida |
| 213 | Pittsburgh | Colin Holba | LS | Louisville |
| 214 | Philadelphia (from Atlanta thru Tennessee) | Elijah Qualls | DT | Washington |
| 215 | Detroit (from New England) | Brad Kaaya | QB | Miami |
| 216c | Dallas (from Kansas City thru New England) | Marquez White | CB | Florida state |
| 217c | Tennessee (from Cincinnati) | Corey Levin | OG | Chattanooga |
| 218c | Kansas City | Leon McQuay | SS | USC |
Seventh round
| 219 | Minnesota (from Cleveland thru San Francisco) | Stacy Coley | WR | Miami |
| 220 | Minnesota (from San Francisco thru Washingfton) | Ifeadi Odenigbo | DE | Northwestern |
| 221 | Oakland (from Chicago thru Arizona) | Shalom Luani | SS | Washington State |
| 222 | Jacksonville | Jalen Myrick | CB | Minnesota |
| 223 | Tampa Bay (from LA Rams thru Miami) | Stevie Tu'ilolovatu | NT | USC |
| 224 | Cleveland (from NY Jets) | Zane Gonzalez | PK | Arizona State |
| 225 | LA Chargers | Ike Rochell | 5T | Notre Dame |
| 226 | Seattle (from Carolina) | David Moore | WR | East Central Oklahoma |
| 227 | Tennessee (from Cincinnati) | Josh Carraway | DE | TCU |
| 228 | Dallas (from Buffalo) | Joey Ivie | DT | Florida |
| 229 | San Francisco (from New Orleans) | Adrian Colbert | CB | Miami |
| 230 | Washington (from Philadelphia) | Josh Harvey-Clemons | SS | Louisville |
| 231 | Oakland (from Arizona) | Jylan Ware | OT | Alabama State |
| 232 | Minnesota | Elijah Lee | LB | Kansas State |
| 233 | Carolina (from Indianapolis) | Harrison Butker | PK | Georgia Tech |
| 234 | LA Rams (from Baltimore) | Ejaun Price | DE | Pittsburgh |
| 235 | Washington | Josh Holsey | CB | Auburn |
| 236 | Tennessee | Brad Seaton | OT | Villanova |
| 237 | Miami (from Tampa Bay) | Isaiah Ford | WR | Virginia Tech |
| 238 | Green Bay (from Denver) | Devante Mays | RB | Utah State |
| 239 | Dallas (from Detroit thru New England) | Noah Brown | WR | Ohio State |
| 240 | Jacksonville (from Miami) | Marquez Williams | FB | Miami (OH) |
| 241 | Tennessee (from NY Giants) | Khalfani Muhammad | RB | California |
| 242 | Oakland | Elijah Hood | RB | North Carolina |
| 243 | Houston | Kyle Fuller | C | Baylor |
| 244 | Oakland (from Seattle) | Treyvon Hester | DT | Toledo |
| 245 | Minnesota (from Kansas City) | Jack Tocho | CB | North Carolina State |
| 246 | Dallas | Jordan Carrell | DE | Colorado |
| 247 | Green Bay | Malachi Dupree | WR | LSU |
| 248 | Pittsburgh | Keion Adams | DE | Western Michigan |
| 249 | Seattle (from Atlanta) | Chris Carson | RB | Oklahoma State |
| 250 | Detroit (from New England) | Pat O'Connor | DE | Eastern Michigan |
| 251c | Cincinnati | Mason Schrek | TE | Buffalo |
| 252c | Cleveland (from Denver) | Matt Dayes | RB | North Carolina State |
| 253c | Denver | Chad Kelly | QB | Mississippi |
