| # | Team | Player | POS | School | Status | |
|---|---|---|---|---|---|---|
| 1 | Cincinnati | Joe Burrow | QB | LSU | Signed | |
| 2 | Washington | Chase Young | DE | Ohio State | Signed | |
| 3 | Detroit | Jeffrey Okudah | CB | Ohio State | Signed | |
| 4 | NY Giants | Andrew Thomas | OT | Georgia | Signed | |
| 5 | Miami | Tua Tagovailoa | QB | Alabama | Signed | |
| 6 | LA Chargers | Justin Herbert | QB | Oregon | Signed | |
| 7 | Carolina | Derrick Brown | DT | Auburn | Signed | |
| 8 | Arizona | Isaiah Simmons | OLB | Clemson | Signed | |
| 9 | Jacksonville | C.J. Henderson | CB | Florida | Signed | |
| 10 | Cleveland | Jedrick Wills | OT | Alabama | Signed | |
| 11 | NY Jets | Mekhi Becton | OT | Louisville | Signed | |
| 12 | Las Vegas | Henry Ruggs | WR | Alabama | Signed | |
| 13 | Tampa Bay (from Indianapolis thru San Francisco) | Tristan Wirfs | OT | Iowa | Signed | |
| 14 | San Francisco (from Tampa Bay) | Javon Kinlaw | DT | South Carolina | Signed | |
| 15 | Denver | Jerry Jeudy | WR | Alabama | Signed | |
| 16 | Atlanta | A.J. Terrell | CB | Clemson | Signed | |
| 17 | Dallas | CeeDee Lamb | WR | Oklahoma | Signed | |
| 18 | Miami (from Pittsburgh) | Austin Jackson | OT | Southern California | Signed | |
| 19 | Las Vegas (from Chicago) | Damon Arnette | CB | Ohio State | Signed | |
| 20 | Jacksonville (from LA Rams) | K'Lavon Chaisson | OLB | LSU | Signed | |
| 21 | Philadelphia | Jalen Reagor | WR | Texas Christian | Signed | |
| 22 | Minnesota (from Buffalo) | Justin Jefferson | WR | LSU | Signed | |
| 23 | LA Chargers (from New England) | Kenneth Murray | ILB | Oklahoma | Signed | |
| 24 | New Orleans | Cesar Ruiz | C | Michigan | Signed | |
| 25 | San Francisco (from Minnesota) | Brandon Aiyuk | WR | Arizona State | Signed | |
| 26 | Green Bay (from Houston thru Miami) | Jordan Love | QB | Utah State | Signed | |
| 27 | Seattle | Jordyn Brooks | ILB | Texas Tech | Signed | |
| 28 | Baltimore | Patrick Queen | ILB | LSU | Signed | |
| 29 | Tennessee | Isaiah Wilson | OT | Georgia | ||
| 30 | Miami (from Green Bay) | Noah Igbinoghene | CB | Auburn | Signed | |
| 31 | Minnesota (from San Francisco) | Jeff Gladney | CB | Texas Christian | Signed | |
| 32 | Kansas City | Clyde Edwards-Helaire | RB | LSU | Signed |
