First round
| # | Team | Player | POS | College |
|---|---|---|---|---|
| Chicago (from Carolina) | Caleb Williams | QB | Southern California | |
| Washington | Jayden Daniels | QB | LSU | |
| New England | Drake Maye | QB | North Carolina | |
| Minnesota (from Arizona - projected trade) | JJ McCarthy | QB | Michigan | |
| LA Chargers | Marvin Harrison | WR | Ohio State | |
| NY Giants | Malik Nabers | WR | LSU | |
| Tennessee | John Alt | OT | Notre Dame | |
| Atlanta | Dallas Turner | ER | Alabama | |
| Chicago | Rome Odunze | WR | Washington | |
| NY Jets | Taliese Fuaga | OT | Oregon State | |
| Arizona (from Minnesota - projected trade) | Brian Thomas | WR | LSU | |
| Denver | Bo Nix | QB | Oregon | |
| Las Vegas | Brock Bowers | TE | Georgia | |
| New Orleans | Olu Fashanu | OT | Penn State | |
| Indianapolis | Quinyon Mitchell | CB | Toledo | |
| Seattle | Byron Murphy | DT | Texas | |
| Jacksonville | Jared Verse | DE | Florida State | |
| Cincinnati | Troy Fautanu | G/T | Washington | |
| LA Rams | Terrion Arnold | CB | Alabama | |
| Pittsburgh | JC Latham | OT | Alabama | |
| Miami | Tyler Guyton | G/T | Washington | |
| Philadelphia | Jackson Powers-Johnson | C | Oregon | |
| Arizona (from Cleveland thru Houston and Minnesota - projected trade)) | Laiatu Latu | DE | UCLA | |
| Dallas | Amarius Mims | OT | Georgia | |
| Green Bay | Nate Wiggins | CB | Clemson | |
| Tampa Bay | Chop Robinson | DE | Penn State | |
| Arizona (from Houston) | Darius Robinson | DT | Missouri | |
| Buffalo | Adonai Mitchell | WR | Texas | |
| Detroit | Cooper Dejean | CB | Iowa | |
| Baltimore | Braden Fiske | DT | Florida State | |
| San Francisco | Ennis Rakestraw | CB | Missouri | |
| Kansas City | Xavier Worthy | WR | Texas |
Second round
| 33 | Carolina | Troy Franklin | WR | Oregon |
| 34 | New England | Jordan Morgan | OT | Arizona |
| 35 | Arizona | Kool-Aid McKinstry | CB | Alabama |
| 36 | Washington | Graham Barton | C/T | Duke |
| 37 | LA Chargers | Johnny Newton | DT | Illinois |
| 38 | Tennessee | Ladd McConkey | WR | Georgia |
| 39 | Carolina (from NY Giants) | Edgerrin Cooper | LB | Texas A&M |
| 40 | Washington (from Chicago) | Xavier Legette | WR | South Carolina |
| 41 | Green Bay (from NY Jets) | Patrick Paul | OT | Houston |
| 42 | Minnesota | Zach Frazier | C/G | West Virginia |
| 43 | Atlanta | Kamari Lassiter | CB | Georgia |
| 44 | Las Vegas | Michael Penix | QB | Washington |
| 45 | New Orleans (from Denver) | Keon Coleman | WR | Florida State |
| 46 | Indianapolis | Kingsley Saumataia | OT | BYU |
| 47 | NY Giants (from Seattle) | Maason Smith | DT | LSU |
| 48 | Jacksonville | Ricky Pearsall | WR | Florida |
| 49 | Cincinnati | Ja'Tavion Sanders | TE | Texas |
| 50 | Philadelphia (from New Orleans) | Chris Braswell | LB | Alabama |
| 51 | Pittsburgh | TJ Tampa | CB | Iowa State |
| 52 | LA Rams | Kris Jenkins | DT | Michigan |
| 53 | Philadelphia | Malachi Corley | WR | Western Kentucky |
| 54 | Cleveland | T'Vondre Sweat | DT | Texas |
| 55 | Miami | Brandon Dorlus | DE | Oregon |
| 56 | Dallas | Jonathan Brooks | RB | Texas |
| 57 | Tampa Bay | Cooper Beebe | G/T | Kansas State |
| 58 | Green Bay | Tyler Nubin | S | Minnesota |
| 59 | Houston | Ruke Orhorhoro | DT | Clemson |
| 60 | Buffalo | Marshawn Kneeland | DE | Western Michigan |
| 61 | Detroit | Zak Zinter | OG | Michigan |
| 62 | Baltimore | Payton Wilson | LB | NC State |
| 63 | San Francisco | Roger Rosengarten | OT | Washington |
| 64 | Kansas City | Kiran Amedgadjie | OT | Yale |
Third round
| 65 | Carolina | Christian Haynes | OG | UConn |
| 66 | Arizona | Javon Foster | OT | Missouri |
| 67 | Washington | Bralen Trice | DE | Washington |
| 68 | New England | Trey Benson | RB | Florida State |
| 69 | LA Chargers | Blake Corum | RB | Michigan |
| 70 | NY Giants | Jaylin Wright | RB | Tennessee |
| 71 | Arizona (from Tennessee) | Junior Colson | LB | Michigan |
| 72 | NY Jets | Ja'Lynn Polk | WR | Washington |
| 73 | Detroit (from Minnesota) | Javon Baker | WR | UCF |
| 74 | Atlanta | Tyler Davis | DT | Clemson |
| 75 | Chicago | Blake Fisher | OT | Notre Dame |
| 76 | Denver | Mo Kamara | LB | Colorado State |
| 77 | Las Vegas | Max Melton | CB | Rutgers |
| 78 | Seattle | Jeremiah Trotter | LB | Clemson |
| 79 | Atlanta (from Jacksonville) | Javion Cohen | OG | Miami |
| 80 | Cincinnati | Luke McCaffrey | WR | Stanford |
| 81 | Seattle (from New Orleans thru Denver) | Christian Mahogany | OG | Boston College |
| 82 | Indianapolis | Jared Wiley | TE | TCU |
| 83 | LA Rams | Cedric Gray | LB | North Carolina |
| 84 | Pittsburgh | Tanner Bortolini | OG | Wisconsin |
| 85 | Cleveland | Javon Bullard | S | Georgia |
| Miami | Pick forfeited | |||
| 86 | Houston (from Philadelphia) | Josh Newton | CB | TCU |
| 87 | Dallas | Sedric Van Pran | C | Georgia |
| 88 | Green Bay | Jaylon Ford | LB | Texas |
| 89 | Tampa Bay | Marshawn Lloyd | RB | Tampa Bay |
| 90 | Arizona (from Houston) | Cole Bishop | S | Utah |
| 91 | Green Bay (from Buffalo) | Jonah Elliss | ER | Utah |
| 92 | Tampa Bay (from Detroit) | Spencer Rattler | QB | South Carolina |
| 93 | Baltimore | Johnny Wilson | WR | Florida State |
| 94 | San Francisco | Jaden Hicks | S | Washington State |
| 95 | Kansas City | Adisa Isaac | DE | Penn State |
| 96 | Jacksonville | Christian Jones | OT | Texas |
| 97 | Cincinnati | Brendan Rice | WR | Southern California |
| 98 | Philadelphia | Calen Bullock | S | Southern California |
| 99 | LA Rams | Will Shipley | RB | Clemson |
| 100 | Washington (from San Francisco) | Brandon Coleman | G/T | TCU |
