*indicates underclassmen
| # | Team | Player | POS | School |
|---|---|---|---|---|
| Cleveland | *Sam Darnold | QB | Southern California | |
| NY Giants | *Josh Rosen | QB | UCLA | |
| San Francisco | Bradley Chubb | DE | North Carolina State | |
| Denver | *Lamar Jackson | QB | Louisville | |
| Indianapolis | *Quenton Nelson | OG | Notre Dame | |
| Chicago | *Minkah Fitzpatrick | DB | Alabama | |
| Cleveland (from Houston) | *Saquon Barkley | RB | Penn State | |
| Tampa Bay | *Derrius Guice | RB | LSU | |
| Cincinnati | *Connor Williams | OT | Texas | |
| Arizona | *Josh Allen | QB | Wyoming | |
| NY Jets | Baker Mayfield | QB | Oklahoma | |
| Washington | Mason Rudolph | QB | Oklahoma State | |
| Miami | *Roquan Smith | LB | Georgia | |
| LA Chargers | *Derwin James | DB | Florida State | |
| Dallas | *Christian Wilkens | DT | Clemson | |
| Oakland | *Josh Jackson | CB | Iowa | |
| Detroit | Harold Landry | DE | Boston College | |
| Buffalo | *Courtland Sutton | WR | SMU | |
| Green Bay | Mike McGlinchley | OT | Notre Dame | |
| Atlanta | *Vita Vea | DT | Washington | |
| Buffalo (from Kansas City) | *Harrison Phillips | DT | Stanford | |
| Baltimore | James Washington | WR | Oklahoma State | |
| Jacksonville | *Ryan Finley | QB | North Carolina State | |
| Tennessee | *Arden Key | ER | LSU | |
| Seattle | *Orlando Brown | OT | Oklahoma | |
| Carolina | Calvin Ridley | WR | Alabama | |
| LA Rams | *Denzel Ward | CB | Ohio State | |
| New Orleans | *Malik Jefferson | LB | Texas | |
| Philadelphia | Martinas Rankin | OT | Mississippi State | |
| Pittsburgh | *Rashaan Evans | LB | Alabama | |
| Minnesota | Biily Price | C/G | Ohio State | |
| New England | *Clelin Ferrell | DE | Clemson |
