| # | Team | Player | POS | School |
|---|---|---|---|---|
| 1 | Tampa Bay | Jameis Winston | QB | Florida State |
| 2 | Cleveland (from Tennessee) | Marcus Mariota | QB | Oregon |
| 3 | Jacksonville | Dante Fowler | OLB | Florida |
| 4 | Oakland | Leonard Williams | DT | Southern California |
| 5 | Washington | Vic Beasley | OLB | Clemson |
| 6 | NY Jets | Amari Cooper | WR | Alabama |
| 7 | Chicago | Danny Shelton | NT | Washington |
| 8 | Atlanta | Todd Gurley | RB | Georgia |
| 9 | New York Giants | Kevin White | WR | West Virginia |
| 10 | St. Louis | Brandon Scherff | G/T | Iowa |
| 11 | Minnesota | Trae Waynes | CB | Michigan State |
| 12 | Tennessee (from Cleveland) | Ereck Flowers | OT | Miami |
| 13 | New Orleans | Bud Dupree | OLB | Kentucky |
| 14 | Miami | Devante Parker | WR | Louisville |
| 15 | San Francisco | Malcom Brown | NT | Texas |
| 16 | Houston | Breshad Perriman | WR | Miami |
| 17 | San Diego | Melvin Gordon | RB | Wisconsin |
| 18 | Kansas City | Andrus Peat | OT | Stanford |
| 19 | Tennessee (from Buffalo thru Cleveland) | Landon Collins | SS | Alabama |
| 20 | Philadelphia | Phillip Dorsett | WR | Miami |
| 21 | Cincinnati | Cameron Erving | OL | Florida State |
| 22 | Pittsburgh | Randy Gregory | OLB | Nebraska |
| 23 | Detroit | DJ Humphries | OT | Florida |
| 24 | Arizona | Arik Armstead | 5T | Oregon |
| 25 | Carolina | La'el Collins | G/T | LSU |
| 26 | Baltimore | Marcus Peters | CB | Washington |
| 27 | Dallas | Kevin Johnson | CB | Wake Forest |
| 28 | Denver | Nelson Agholor | WR | Southern California |
| 29 | Indianapolis | Damarious Randall | FS | Arizona State |
| 30 | Green Bay | Stephone Anthony | LB | Clemson |
| 31 | New Orleans (from Seattle) | Byron Jones | CB | UConn |
| 32 | New England | Shane Ray | LB | Missouri |
